The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading ...

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to ...

A proof-of-principle study published in Nature Materials shows that gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells. (Photos, diagram ...

Scientists have designed a slimmed-down CRISPR protein, enEbCas12a, that still packs a punch in precision editing. Its small size means it can hitch a ride in a harmless virus, delivering edits ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

The new tool—called LF N -Acr/PA—uses a protein-based delivery system to ferry anti-CRISPR proteins into human cells rapidly and efficiently. While natural Type II anti-CRISPR proteins (Acrs) are ...

A team of researchers led by Alan Davidson at the University of Toronto have discovered a small protein that can disassemble a stable bacterial CRISPR-Cas7 complex without using adenosine ...

To the research team working to save him, KJ Muldoon was first known only as Patient Eta. But within months, KJ’s name — and ...

All of the previously known CRISPR immune systems protect bacteria by deactivating genes from an invading virus. Now, a recently discovered CRISPR protein, called Cas12a2, has been found to act as a ...